Transient elastography is useful in diagnosing biliary atresia and predicting prognosis after hepatoportoenterostomy
Hepatology Jun 10, 2018
Wu JF, et al. - Forty-eight cholestatic infants with direct bilirubin level >1 mg/dL were recruited in order to examine the utility of transient elastography (TE) for diagnosing biliary atresia (BA) in cholestatic infants and predicting the outcome of BA. Using the METAVIR score, the researchers evaluated liver histology using liver biopsies from thirty-six subjects and graded fibrosis status. The diagnosis of BA could be facilitated by liver stiffness measurement (LSM) assessment during the workup of cholestatic infants. In infants with BA, LSM post-hepatoportoenterostomy (HPE) could predict complications and the need for early liver transplantation (LT).
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