Valero-Rubio D, et al. - The transcriptomic effect of FUCA1 knock-down was analyzed by the experts in the keratinocytes for better understanding the pathogenesis of skin lesions affecting fucosidosis patients. Results demonstrated that dysfunctions in common aetiological overlapping molecular cascades could cause the fucosidosis-related skin lesions (e.g. angiokeratoma) and those of other diseases (e.g. psoriasis).