Irwin SL, et al. - In an open-label pilot study, researchers determined the feasibility, tolerability, and patient acceptability of single-pulse transcranial magnetic stimulation (sTMS) for migraine prevention in adolescents (aged 12-17 years). Twenty-one participants used sTMS twice daily in a preventative fashion, as well as additional pulses as needed acutely. Observations suggest that, for migraine in adolescents, sTMS is a feasible, well-tolerated, and acceptable nonpharmacologic preventive treatment.