Witberg G, et al. - Researchers analyzed data from randomized controlled trials (RCTs) and propensity score matched (PSM) observational studies reporting transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR) in patients who are at low surgical risk, focusing on all-cause mortality, stroke, myocardial infarction, bleeding, and various procedural complications. This analysis included 6 studies (2 RCTs and 4 PSM studies) totaling 3,484 patients. TAVR seemed to be related to increased mortality risk in patients who were at low surgical risk and SAVR was recommended to be considered as the treatment of choice for these patients.