Fried JW, Bloom DA, Hurley ET, et al. - A double-blinded randomized controlled trial was designed to assess the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patella tendon-bone (BTB) anterior cruciate ligament reconstruction (ACLR) with regard to post-operative hemarthrosis, pain, opioid consumption, quadriceps atrophy, and activation. Researchers included a total of 110 patients who had undergone ACLR with BTB autograft. They randomized individuals equally to the control and experimental groups. This study’s findings demonstrate that IV TXA in patients who undergo ACLR with BTB autograft does not significantly impact perioperative blood loss, postoperative hemarthrosis, or postoperative pain levels. There were no significant variations in early post-operative recovery regarding ROM or quadriceps reactivation.