Zimmerman JJ, Banks R, Berg RA, et al. - In order to report the trajectory of mortality as well as health-related quality of life morbidity for pediatric population with community-acquired septic shock, the Life After Pediatric Sepsis Evaluation investigation was performed. Researchers carried out this prospective, cohort-outcome analysis in 12 academic PICUs in the United States from 2013 to 2017. Overall 389 children who were critically ill, with mean age 7.4 ± 5.8 years, were enrolled. These participants were suffering from community-acquired septic shock necessitating vasoactive-inotropic support. At PICU admission, the median (Q1–Q3) Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction scores were identified to be 11.0 and 9.0; and durations of PICU and hospital stay were reported to be 9.4 days and 15.7 days. This work affords the first longitudinal report of long-term mortality as well as clinically important, health-related quality of life morbidity in children struggling community-acquired septic shock. The reported in-hospital mortality was 9%, and significant, health-related quality of life decline from baseline was evident in 35% of survivors, that persisted at least 1 year after hospitalization for septic shock.