Trajectories of growth associated with long-term stimulant medication in the multimodal treatment study of attention-deficit/hyperactivity disorder
Journal of the American Academy of Child & Adolescent Psychiatry Oct 01, 2019
Greenhill LL, Swanson JM, Hechtman L, et al. - In the Multimodal Treatment Study of Attention-Deficit/Hyperactivity Disorder, researchers sought to examine how long-term stimulant treatment influence standardized height, weight, and body mass index trajectories from childhood to adulthood. They assessed 568 children with DSM-IV ADHD−combined type at baseline (aged 7.0–9.9 years) and 258 classmates (local normative comparison group [LNCG]) 8 times over 16 years (final mean age = 24.7). Compared with children who were negligibly medicated and the LNCG, those with ADHD who received stimulant treatment consistently over 16 years showed changes in height trajectory, a reduction in adult height, and an increase in weight and body mass index.
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