Valenti R, et al. - The physicians wished to figure out whether increased overall small vessel disease (SVD) injury on MRI corresponds to worse global brain connectivity in cerebral amyloid angiopathy (CAA). They illustrated that an increased burden of SVD neuroimaging markers corresponds to more reductions in global brain connectivity, indicating a possible cumulative effect of overall SVD markers on disrupted physiology. Global network efficiency (GNE) was associated with some components of the score, specifically cortical superficial siderosis (cSS) and moderate-severe white matter hyperintensities (WMH).