Kuzkov VV, et al. - Carotid endarterectomy (CEA) is effective for the prevention of stroke, yet can be associated with a postoperative cognitive dysfunction (POCD) that may be affected by the type of anesthesia. Herein, total intravenous anesthesia (TIVA) with propofol was compared with volatile induction and maintenance of anesthesia (VIMA) with sevoflurane, in terms of impacts on cerebral tissue oxygen saturation (SctO₂) and POCD. In CEA, VIMA with sevoflurane vs propofol anesthesia might preserve oxygenation in the contralateral hemisphere, suppress an asymmetry of cerebral oxygenation, and improve the early postoperative cognition.