Pereira A, Busch AS, Solares F, et al. - This longitudinal study was undertaken to determine whether pubertal timing is correlated with BMI as well as total and central adiposity in pre-pubertal Chilean boys. Four hundred ninety-four boys from the Growth and Obesity Chilean Cohort Study were followed starting from birth and throughout puberty including five pre-pubertal visits. Using a survival- and logistic regression models, the connection between BMI, obesity (BMI SDS ≥ 2) and central adiposity (waist circumference ≥ 90th centile) with precocious puberty and age at gonadarche was analyzed. The finding confirms the correlation of pubertal timing and precocious gonadarche in boys with BMI SDS and obesity, respectively. Early action to regulate the obesity epidemic may be effective in reducing the adverse effect on later health.