Birmingham AR, et al. - The effectiveness and potential benefits of topical tranexamic acid (TXA) in the management of acute epistaxis were investigated. In this work, patients with acute epistaxis treated with topical TXA or standard care did not demonstrate a significant difference in Emergency Department (ED) length of stay (LOS). However, findings seemed supporting the association of TXA with a reduction in resource utilization, indicating its potential for providing more effective bleeding control.