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Tonsillectomy plus steroid pulse therapy is the most effective treatment in adult patients with C-Grade I IgA nephropathy, and the weight of the extracted palatine tonsils and Yamamoto scale have no significant correlation with the effects of this treatment

Auris Nasus Larynx Jan 24, 2019

Kondo N, et al. - Investigators assessed 118 candidates of age more than 18 years to examine the clinical factors associated with a positive response to tonsillectomy plus steroid pulse therapy (TSP) for immunoglobulin A nephropathy (IgAN). Using both univariate and multivariate analysis, they observed 56.8% of CR rate in all cases with respect to the C-Grade. They noted CR rate of C-Grade І (73.4%) cases was significantly greater than that of C-Grade II (39.0%) and C-Grade III individuals (30.8%). Fibrosis/hyalinization of the stroma of palatine tonsils revealed the statistical significance of C-Grade III cases in the univariate analysis only. They did not notice any relation of Yamamoto scale and weight of the extracted palatine tonsils with the clinical effect of TSP.
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