Timing of cow’s milk or cow’s milk formula introduction to the infant diet and atopic risk in children: A systematic review and meta-analysis
Clinical Reviews in Allergy and Immunology Nov 28, 2019
Yuan M, Tan M, Moore D, et al. - Researchers analyzed the evidence reporting the influences of timing of cow’s milk (CM) or cow’s milk formula (CMF) introduction to the infant diet on atopic diseases development during childhood. Through May 30, 2019, they explored Pubmed, Embase, CINAHL, Cochrane CENTRAL, and CNKI. This analysis included 45 studies from 20 countries. They found no links between early introduction of CM or CMF and the risk of asthma, wheeze, and eczema or atopic dermatitis when performed meta-analyses using adjusted data. Overall, concerning the link between early CM or CMF introduction and risk of allergic diseases, there was quite little high-quality evidence to allow for definitive conclusions. The particular gaps in knowledge for public guidance about CM or CMF feeding practice in an early stage of life, especially prior to 3 months of age, were highlighted in this analysis.
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