Maddaloni E, et al. - Researchers conducted this post-hoc analysis to investigate the long-term risk of microvascular complications in people registered in the UK Prospective Diabetes Study (UKPDS), according to their diabetes autoimmunity status. UKPDS participants who had diabetes autoantibody measurements available and were included without previous microvascular events. Among the 5,028 candidates involved, 564 had latent autoimmune diabetes and 4,464 had T2D. The composite microvascular outcome occurred in 1,041 participants after median 17·3 years (IQR 12·6–20·7) of follow-up. Data reported that the incidence for the composite microvascular outcome was 15·8 per 1,000 person-years in latent autoimmune diabetes and 14·2 per 1,000 person-years in T2D. At the onset of diabetes, adults with latent autoimmune diabetes have a lower risk of microvascular complications followed by a higher risk of complications later on than adults with T2D, secondary to worse glycaemic control. Implementing rigorous glycaemic control from the time of diagnosis could lessen the risk of later microvascular complications in adults with latent autoimmune diabetes.