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Time to pregnancy after a prepregnancy very-low-energy diet program in women with obesity: Substudy of a randomized controlled trial

Fertility and Sterility Oct 22, 2020

Price SA, Sumithran P, Prendergast LA, et al. - Researchers performed a substudy of a two-arm parallel group randomized controlled trial with the aim to ascertain how a prepregnancy very-low-energy diet (VLED) program affects time to pregnancy in women with obesity. Through a social media platform, they performed recruitment of 164 normoglycemic women with body mass index 30–55 kg/m 2, aged 18–38 years, and planning pregnancy. Allocation of the participants was done to a 12-week standard dietary intervention (SDI) or modified VLED. Findings revealed reduction in time to pregnancy in correlation with a VLED program that achieves substantial weight loss before conception vs an SDI in women with obesity.

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