Ueshima D, et al. - In this systematic review of eight studies with 6,596 women and 7,204 men, researchers assessed transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR) in terms of the time-related survival advantage with regard to the patients' risk and sex. They included studies that reported clinical outcomes of men and women undergoing TAVR or SAVR. Taking into account average patient's risk score, two groups of studies were formed. A selective mortality benefit was seen with TAVR vs SAVR among women patients; high surgical risk patients in particular demonstrated this sex-based TAVR benefit after 1 year following the procedure. This benefit was still seen at the 2 year mark.