Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression
Metabolism Aug 12, 2017
Gong Y, et al. – The scientists aimed to explore the impact of thyroid stimulating hormone (TSH) on hepatic proprotein convertase subtilisin/kexin type 9 (PCSK9) expression and low–density lipoprotein cholesterol (LDL–c) metabolism. They discovered a regulating role of TSH on hepatic PCSK9 expression, which further contributes to a higher LDL–c level.
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