Han Y, et al. - In the Ma'anshan Birth Cohort study, a population-based prospective study in China, the researchers investigated relationships of maternal thyroid autoantibody positivity in the first and the second trimesters with the risk of hypertensive disorders of pregnancy (HDP). They recruited 3474 pregnant women between May 2013 and September 2014. In both the first and the second trimesters in 2893 pregnant women, thyroid autoantibodies, including antithyroperoxidase autoantibody (TPOAb) and antithyroglobulin autoantibody (TgAb), as well as thyroid function tests, were measured. According to the findings obtained, TPOAb positivity and TgAb positivity in the first trimester were correlated with an increased risk of HDP. Findings revealed that these associations were also seen among euthyroid women.