Ozkan Y, Kandemir H, Sapmaz SY, et al. - Researchers investigated pediatric patients diagnosed with OCD and a healthy control group for a particular oxidative stress marker, thiol/disulfide homeostasis, using a new, comparatively inexpensive, easily calculated, easily accessible, repeatable, and fully automated method. In this study, this subject in pediatric patients with OCD is addressed for the first time and further insight into the etiopathogenesis and treatment of pediatric OCD is provided. Assessment of children with OCD (n = 35, 52.2%) (drug free, comorbidity free) between 11 and 18 years of age and age- and gender-matched healthy controls (n = 32, 47.8%) revealed significant disturbances in thiol/disulfide homeostasis in pediatric OCD patients. Findings suggest a possible role of thiol/disulfide homeostasis in the etiopathogenesis of pediatric OCD.