Zaki AM, Nada AS, Elshahed AR, et al. - In the present study, the researchers sought to analyze the serum zinc levels in vitiligo patients relative to healthy controls and whether a link existed between disease severity and serum zinc levels. Fifty patients with vitiligo (Group A) and fifty age and sex-matched healthy controls (Group B) were enrolled and serum zinc level was assessed using atomic absorption spectrophotometry and outcomes were compared and correlated to each other and to disease severity and extension. There is a significant association between vitiligo and serum zinc levels. Serum zinc levels were negatively associated with vitiligo disease severity and extension. Supplementation and use of zinc may be of potential significance in developing guidelines for treating vitiligo.