Okui A, Konomi U, Kanazawa T, et al. - In this retrospective chart review involving 53 patients (mean age was 69.0 ± 9.5 years), researchers studied the impacts of local injection of basic fibroblast growth factor (bFGF) on age-related vocal atrophy and the impact of age on phonological results. Participants in the study were patients who presented to the Tokyo Voice Center over 3 years starting in April 2014 who had hoarseness caused by age-related vocal fold atrophy. After injection, Voice Handicap Index (VHI), maximum phonation time (MPT), jitter, shimmer, and pitch range improved, and the effects lasted for 6 months. VHI and MPT exhibited improvement at 3 and 6 months after injection in those over 70 years of age. Furthermore, there was no significant difference in the degree of improvement in VHI and MPT between those older than 70 years and those younger than 70. For both early and late elderly patients suffering of vocal fold atrophy, regenerative treatments dependent on bFGF single injection was effective and safe.