Gedik O, Doğan R, Babademez MA, et al. - Via dividing 32 rodents into four groups (Group 1: Noise, Group 2: Noise + Metformin, Grup 3: Metformin, Grup 4: Control), researchers studied the healing impact of metformin on noise induced hearing loss (NIHL) by measuring audiological, biochemical and histological parameters. After basal measurements, broadband noise was applied to Group 1 and Group 2. According to results, the ABR thresholds of Group 2 decreased significantly on day 7 and day 14 compared with day 1. Group 2 distortion product otoacoustic emission values were significantly higher on the 7th and 14th days than the postnoise levels. Compared with the other groups, DNA damage, TOS and OSI values of Group 1 were significantly higher. There was no significant difference between the groups being exposed to noise and the control group in histopathological results of the study. Findings suggested the early Metformin treatment period would have a therapeutic effect on NIHL.