Alulis S, et al. – The aim of this work was to conduct a systematic review and meta–analysis of family–based interventions for child and adolescent obesity to distinguish the theoretical frameworks applied, therefore understanding how theory is used in practice. In context of the findings, the designs of family–based interventions reveal numerous inconsistencies and a significant void between research results and health care practice. Based on the analysis, this article proposes three themes to be applied as target points when designing future interventions and when selecting theories for the development of solid, theory–based frameworks for application. The themes are: (1) age of target group, (2) intervention objective, and (3) self–efficacy and readiness for change.