Sekerci CA, et al. - Experts gauged the impact of intradetrusor botulinum neurotoxin-A injection (iBoNT-Ai) on urine brain-derived neurotrophic factor (BDNF) levels in children with neurogenic detrusor overactivity (NDOA) due to myelodysplasia. In children with NDOA due to myelodysplasia urine BDNF was hardly suggested to be a follow-up marker. Nonetheless, authors noted its obscure role in treatment planning. Statistically high urine BDNF levels were seen in only patients with a bladder compliance of 5 mL/cmH₂O or less at the postoperative urodynamics vs the ones above 5 mL/cmH₂O, suggesting high urine BDNF to predict treatment failure.