Notay M, et al. - In this prospective study, researchers ascertained if there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha [ammonia-oxidizing bacteria], a topical probiotic. For this investigation, high-resolution photographs were obtained in 29 candidates at baseline and after using topical Nitrosomonas eutropha for 7 days. In terms of reducing the appearance of wrinkles, Nitrosomonas eutropha might have aesthetic advantages. In addition, a statistically significant improvement was noted in pigmentation of the forehead and glabella in the higher concentration group. Larger studies are needed with longer treatment and follow-up periods.