Patel UA - Researcher conducted a retrospective review on patients at two tertiary care academic hospitals by a single surgeon to contrast intraoperative, postoperative, functional, and oncologic results of the submental island pedicled flap (SIPF) to the radial forearm free flap (RFFF). Between 2004 and 2016, consecutive patients who had cancer resection and reconstruction with SIPF or RFFF have been involved. Participants in the study were 146 individuals (57 SIPF; 89 RFFF). Oral cavity, with a minority in the oropharynx, paranasal sinuses, or external eyes, was the most prevalent primary site. Compared with 48 cm² for the RFFF, mean area of the SIPF was smaller at 28 cm². Compared with 9 hours for RFFF, operative time for SIPF was shorter at 6.5 hours. The SIPF significantly reduces both the operating time and the hospital stay. With no contraindication to the SIPF, functional and oncological findings are identical. The SIPF is a good first-line option for reconstruction of head and neck.