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The stool microbiota at neutrophil recovery is predictive for severe acute graft versus host disease after hematopoietic cell transplantation

Clinical Infectious Diseases Aug 25, 2017

Golob JL, et al. – Given the association of risk for death from graft–versus–host–disease (GVHD) with low bacterial diversity in the stool microbiota early after transplant, this study sought to assess the association of the relative abundance of sequence reads from bacterial taxa in stool samples over time with GVHD risk. In the study population, the stool microbiota around the time of neutrophil recovery post–hematopoietic cell transplantation (HCT) was predictive of subsequent development of severe acute GVHD.
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