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The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma

Head & Neck May 31, 2021

Mooney CP, Clark JR, Shannon K, et al. - Given regional metastasis of head and neck cutaneous squamous cell carcinoma (HNcSCC) can be detected in either parotid and/or cervical lymph nodes, researchers herein used an institutional database to find out if prognosis varied between parotid and cervical nodal metastases. They identified 535 patients with regional metastasis from HNcSCC with median follow-up of 26.4 months (3–255 months). Among these, parotid metastasis was present in 235, neck metastasis was detected in 96 patients, and 204 patients had both. Findings demonstrated worse outcomes in relation to regional metastasis of HNcSCC to the neck vs metastasis to the parotid alone.

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