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The serotonin transporter gene polymorphisms and risk of ischemic stroke

Cerebrovascular Diseases Apr 09, 2018

Mortensen JK, et al. - Researchers examined the link between polymorphisms in the serotonin transporter (SERT) gene and the risk of ischemic stroke/transitory ischemic attack (TIA) among Caucasian ischemic stroke patients/TIA from Aarhus University Hospital, Denmark and healthy controls. A possible relation was brought to light between the presence of the high expression SERT genotype (LALA) with a lower risk of ischemic stroke/TIA. Yielded data raised interesting considerations for future personalized medicine potential. It was noted that the lower OR estimates correlated with the high-expression genotype were consistent across all stroke subtypes.
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