Xie X, et al. - The bifold aim of this research was to elucidate the roles of genetic factors in Kawasaki disease (KD) and to investigate the potential genetic biomarkers of KD. It was displayed that gene polymorphisms of ACE, BLK, CASP3, CD40, FCGR2A, FGβ, HLA-E, IL1A, IL6, ITPKC, LTA, MPO, PD1, SMAD3, CCL17 and TNF could exert an impact on the KD susceptibility. The genetic variations in BTNL2, CASP3, FCGR2A, FGF23, FGβ, GRIN3A, HLA-E, IL10, ITPKC and TGFBR2 could present as biomarkers of coronary artery lesions (CALs) in KD.