de Veld L, Wolberink IM, van Hoof JJ, et al. - This research sought to ascertain the prevalence of tobacco smoking and illicit drug use among Dutch adolescents admitted to hospital for acute alcohol intoxication treatment. Researchers further explored an association between illicit drug use and specific characteristics of intoxication, such as blood alcohol concentration (BAC) and duration of reduced consciousness. Between 2007 and 2017, the national Dutch Paediatric Surveillance Unit was applied to prospectively register cases of acute alcohol intoxication. In this study, 5,322 cases that met the inclusion criteria were reported during the period 2007–2017. This study’s findings demonstrated that evaluating smoking and illicit drug use among adolescents admitted for acute alcohol intoxication is important in acute cases of intoxication, for outpatient follow-up, and for the purposes of prevention. The results revealed that the association between simultaneous illicit drug use and a lower BAC is of relevance for pediatricians’ attempts to diagnose acute intoxication. It is important to be aware that adolescents’ alcohol consumption, tobacco, and illicit drug use are related and, ultimately, elevate the odds of using other substances.