Yorgancı A, Ozturk FH, Hancerliogullari N, et al. - Researchers conducted a case-control study of women hospitalized for singleton first-trimester pregnancy terminations due to missed abortion, anembryonic pregnancy, and inevitable abortion in order to measure serum levels of podocalyxin (PODXL) in recurrent miscarriages as a marker of vascular endothelial dysfunction. They included a total of 24 patients admitted for the first pregnancy termination, 39 patients admitted for recurrent pregnancy loss (RPL), and 25 fetal cardiac activity positive patients as the control group. Findings revealed higher serum levels of PODXL in recurrent miscarriage patients relative to both normal pregnancies and first-time miscarriages. They suggest a possible involvement of maternal endothelial dysfunction in recurrent pregnancy losses.