The role of serum nuclear factor erythroid 2-related factor 2 in childhood bronchial asthma
Journal of Asthma Feb 13, 2019
Youness ER, et al. - Researchers analyzed 60 asthmatic children and 60 controls (age from 6-16 years) to examine the relationship of bronchial asthma with serum nuclear factor erythroid 2–related factor2 (NRF2) and its association with disease severity among Egyptian adolescents. They calculated the antioxidant markers including superoxide-dismutase (SOD), glutathione peroxidase (GPX) and NRF2 in blood and serum of both the groups. A lower value of mean serum NRF2 and GPX were observed in the asthmatic group as compared to the controls. They noticed no significant variation in SOD concerning the severity of bronchial asthma. Overall, they suggested low NRF2 as the only predictor of the severity of bronchial asthma.
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