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The role of preoperative computerized tomography (CT) scan of the pelvis and groin in the management of clinically early staged vulva squamous cell carcinoma

Gynecologic Oncology Jan 31, 2020

Pounds R, O'Neill D, Subba K, et al. - Researchers determined whether preoperative CT scan, the imaging option in their cancer centre, changes the overall course of vulvar squamous cell carcinoma (VSCC) management in those patients without clinical proof of groin lymphadenopathy. Of 225 patients having VSCC who had staging surgery within a regional tertiary gynaecological cancer centre, 116 (56.6%) underwent preoperative CT imaging. For identifying groin lymphatic metastasis, the sensitivity and specificity of cross-sectional imaging were 59.1% and 77.8%, respectively; while the positive predictive value (PPV) was 61.9% and negative predictive value (NPV) was 75.7%. For the detection of inguinal node metastasis, the sensitivity, specificity, PPV and NPV of CT scan in patients who had sentinel inguinal nodes biopsy were 30.0%, 85.7%, 33.3% and 83.7%, respectively. Experts concluded that preoperative CT scan may be omitted in early stage VSCC before surgical staging as it exerts no influence on overall management and surgical results.
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