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The role of multimicronutrient supplementation in pediatric HIV management in Nigeria: A randomized controlled study

Journal of the Pediatric Infectious Diseases Society Mar 26, 2020

Esiovwa R, , et al. - Researchers compared the immunologic and hematologic effects of 3 multimicronutrient supplement in human immunodeficiency virus–positive children in Lagos, Nigeria via performing a double-blind, randomized controlled study including 190 children, aged 5–12 years, in Lagos, Nigeria. They assigned 64, 63, and 63 participants to receive multimicronutrient group A, B, or C, respectively, for 6 months. Supplements A, B, and C contained 7 micronutrients at the recommended daily allowance (RDA) (comparable to standard-of-care multivitamin), 22 micronutrients at the RDA, and 22 micronutrients at 3 times the recommended daily allowance (3RDA), respectively. Outcome analysis revealed equivalent effects. After 6 months of supplementation, the groups showed no significant differences in mean CD4 count. All 3 groups showed significant rise in hemoglobin concentration, but with no between group differences.

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