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The role of elective neck dissection in high-grade parotid malignancy: A hospital-based cohort study

The Laryngoscope Sep 05, 2019

Harbison RA, Gray AJ, Westling T, et al. - In patients with cN0, high-grade parotid carcinoma, the researchers explored the connection between elective neck dissection (END) and survival. Between January 1, 2004 and December 31, 2013, patients diagnosed with cN0, high-grade parotid cancer were included. Overall, there were 1,547 patients, with a median follow-up time of 48 months. According to this retrospective, multicenter cohort study, END had no statistically significant impact on survival among cN0 patients with high-grade parotid cancer when considering receipt of adjuvant therapy and confounding. There was no difference in 3-year survival among patients with parotidectomy and adjuvant radiation stratified by receiving END nor did END have a statistically significant effect on survival in subgroups of mucoepidermoid carcinoma, adenocarcinoma, high-risk histology, high-T-stage or academic center therapy. The strongest effect on mortality was parotidectomy and adjuvant radiotherapy. In prospective studies, the role of END in survival and locoregional control remains to be further clarified.
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