Helal MH, et al. - In this prospective analysis, researchers assessed if contrast-enhanced spectral mammography (CESM) could identify malignancy in the breast of cancer patients following surgery. The study sample consisted of 76 women after breast cancer operations. Following intravenous injection of contrast agent, CESM was conducted with low (22–33 kVp) and high (44–49 kVp) energy exposures. Findings revealed that CESM improved mammography performance with a 91.17% sensitivity, 75% specificity, 77.5% positive predictive value, 90% negative predictive value and 82.85% accuracy. With traditional mammography, sensitivity was 50%, specificity was 22%, positive predictive value was 37.7%, negative predicative value was 32%, and accuracy was 35.7%. Overall, the authors concluded that CESM is a reliable method that could be used in breast cancer screening following surgery with the traditional mammogram.