Shao S, Luo C, Zhou K, et al. - A prospective cohort study was done between June 2015 and April 2018 with standardized data collection including 393 Kawasaki disease (KD, an acute general vasculitis of unknown etiology that principally occurs in infants and children under five years of age) patients aged 1 month to 125 months to evaluate the efficiency of age-specific N-terminal pro-brain natriuretic peptide (NT-ProBNP) values in prognosticating intravenous immunoglobulins (IVIG resistance in KD and to ascertain the best cutoff values of NT-ProBNP for various age groups. The level of NT-ProBNP in all KD patients was significantly greater in the IVIG-resistance vs IVIG-response group. These findings was comparable in the subgroups except for patients older than six years. Thus, for the prognostication of IVIG resistance in KD patients, NT-proBNP is a complementary laboratory marker, especially for those younger than one year. Applying age-specific cutoff values is more accurate compared with one value for all ages.