Bjornstad P, et al. - In adults with type 1 diabetes (T1D), researchers described the connections between plasma biomarkers of kidney injury and intrarenal haemodynamic function (glomerular filtration rate [GFR], effective renal plasma flow [ERPF], renal vascular resistance [RVR]). Study participants included patients with longstanding T1D, among whom 44 were diabetic kidney disease (DKD) resistors and 22 had DKD, in addition to 73 control participants. According to findings, elevated neutrophil gelatinase-associated lipocalin (NGAL) is correlated with intrarenal haemodynamic dysfunction in T1D, while elevated NGAL and β2 microglobulin (B2M) are related to intrarenal haemodynamic dysfunction in adults without T1D. These data can define a diabetes-specific interplay between intrarenal haemodynamic dysfunction and tubular injury.