Ohira M, Watanabe Y, Yamaguchi T, et al. - Findings demonstrate usefulness of preoperative insulin-like growth factor-1 (IGF-1) measurement in predicting successful weight loss after laparoscopic sleeve gastrectomy (LSG). In addition, preoperative serum IGF-1 levels were identified to be associated with decreased body fat mass and maintaining skeletal muscle mass post-LSG.

• This is a retrospective review of 72 patients with obesity who had LSG and were followed up for 12 months.

• A significant reduction in body weight was conferred by LSG.

• Post-LSG, reduction was evident in both body fat mass and skeletal muscle mass.

• Significant correlation of preoperative serum IGF-1 levels with the following was evident: total weight loss percentage, alterations in skeletal muscle mass, and body fat mass following LSG.