Badley EM, Zahid S, Wilfong JM, et al. - This study was carried out to ascertain if an apparent relationship between hand osteoarthritis (OA) and adiposity is explained by the presence of OA at other joint sites. Researchers obtained data from the Canadian Longitudinal Study on Aging, first cycle, Comprehensive Cohort. In this analysis, a total of 18,279 respondents aged 45-85 years were included, and asked separate questions about doctor-diagnosed OA in the hand, hip, or knee. They used multinomial logistic regression to explore the relationship between all combinations of hand, hip, and knee OA and body mass index (BMI) and waist to height ratio. This study’s findings demonstrate that apparent relationships between hand OA and BMI may be explained by concurrent OA at other joint sites. According to the findings, recognizing that OA is a multi-joint disease is crucial for studies of the associations of adiposity with OA in a particular joint, particularly the hand. The relationship between knee OA and BMI seems to be distinct from those for OA at other joint sites.