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The relation between fracture activity and bone healing with special reference to the early healing phase - A preclinical study

Injury Oct 14, 2020

Windolf M, Ernst M, Schwyn R, et al. - Researchers stabilized tibial defects of seven Swiss mountain sheep with a dynamizable bone fixator, which allowed for defined interfragmentary motion by limiting the maximum axial displacement. They assessed callus size over time from x-rays. They further evaluated the ultimate torsional strength of the healed defects after euthanasia. The results indicate a positive impact of, within limits, frequent fracture stimulation on bone healing and implies utility of the mechanical environment in the direct post-operative healing phase. The data suggest the concept of direct postoperative weight-bearing. Nevertheless, needs clinical confirmation and must be considered within the full clinical context including the risk for fixation failure from overloading.

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