The related factors of sleep benefit in Parkinson’s disease: A systematic review and meta-analysis
PLoS Neglected Tropical Diseases Mar 17, 2019
Zhong Rui Z, et al. - In Parkinson’s disease (PD), researchers assessed the likely related factors of sleep benefit (SB) in this systematic review and meta-analysis. Findings revealed three related factors linked to SB: the duration of PD (mean deviation (MD) 1.22, 95% CI: 0.21–2.23), sleep efficiency (MD -4.48,95% CI: -7.24- -2.44), and on-state MDS-UPDRS-Ⅲ total score (MD 3.05, 95% CI: 0.53–5.57). Outcomes suggest a higher likelihood for long duration of PD, low sleep efficiency, and high MDS-UPDRS-Ⅲ total score among PD patients with SB. This study is helpful in enhancing the understanding regarding SB in PD and its underlying mechanisms.
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