Moro ET, Ferreira MAT, dos Santos Gonçalves R, et al. - Given that administration of intrathecal morphine to avert postoperative pain following orthopedic surgery is often related to side effects, and therefore, researchers assessed the impact of dexamethasone or ondansetron, vs placebo, to decrease the development of these undesirable effects and, as a result, to improve the quality of recovery based on patient’s perspective. This study included 135 patients who received spinal anesthesia using bupivacaine and morphine for lower extremity orthopedic surgery. These patients were randomized to receive IV dexamethasone, ondansetron, or saline. A quality of recovery questionnaire was completed on the morning after surgery. As per findings, no improvement in the quality of recovery was afforded by ondansetron or dexamethasone in patients who underwent lower limbs orthopedic surgery under spinal anesthesia using intrathecal morphine.