Ye LL, et al. - In patients with hypopharyngeal and/or supraglottic carcinoma, researchers examined the prognostic ability of the clinicopathological parameters of primary lesions for predicting cervical lymph node metastasis. Participants in the study were 127 subjects with squamous cell carcinomas originating in the hypopharyngeal and/or supraglottic regions. In hypopharyngeal and supraglottic carcinomas, the tumor depth of the primary lesion is a strong predictor of cervical lymph node metastasis. Elective neck dissection should be used for patients with a tumor depth reaching 4.5 mm in cases with clinically negative nodal status. For patients with a tumor depth less than 1.0 mm, regular outpatient follow-up is suggested. Close follow-up or preventive therapy between 1.0 and 4.5 mm should be considered.