Song L, et al. - Researchers sought to determine the value of lymphocyte-to-monocyte ratio (LMR) prognostic prediction in high-risk papillary thyroid carcinoma (PTC) patients. They randomized 224 PTC high-risk cases at West China Hospital into a training set (112 cases) and testing set (112 cases) while including 48 cases in Shang Jin Nan Fu Hospital as the external validation set. Outcomes revealed the correlation of a lower preoperative LMR with larger tumor size, advanced N and M stages, and an increased number of multiple PTC cases in the training, testing, and validation sets. They developed nomograms for prophesying the 5-year mortality and PTC recurrence taking into account the risk factors in the training set and validated them in the independent testing and validation sets. An independent prognostic value of the preoperative LMR was identified supporting its incorporation into the two nomograms with other risk factors to predict overall survival and PTC-free survival for individual patients.