Wang M, et al. - In a relatively large clinical setting of 56 patients with primary angiosarcoma (AS), rare and highly malignant type of soft tissue sarcoma derived from vascular endothelial cells, researchers, for the first time, analyzed the six pretreatment inflammatory indexes including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, systemic immune-inflammation index, lactate dehydrogenase (LDH) and ALP. For this investigation, they retrospectively enlisted patients diagnosed with primary AS at West China Hospital between August 2009 and July 2016. According to results, in univariate analyses, the low tumor grade, tumor size < 5 cm, metastatic status, surgical treatment and low level of monocyte-to-lymphocyte ratio, NLR and LDH were associated with better survival result. High levels of NLR and LDH were selected as independent prognostic factors in multivariate analyses. In patients with primary AS, the elevated pretreatment levels of NLR and LDH as prognostic markers were identifies.