Bösch F, Schallhorn S, Miksch RC, et al. - Since there is a lack of a blood marker which reliably predicts sepsis and related mortality, so researchers undertook this prospective analysis to assess presepsin and endotoxin vs established blood markers among patients undergoing emergency visceral surgery for abdominal infection. This study involved 31 patients. Experts applied the Sepsis-2 and Sepsis-3 definitions of sepsis. Of blood markers analyzed (presepsin, endotoxin, C-reactive protein, procalcitonin (PCT), interleukin 6 (IL-6), white blood count), the highest area under the curve, sensitivity, as well as specificity for the prediction of sepsis occurrence was afforded by presepsin. As opposed to endotoxin and previously established blood markers (ie, PCT, IL-6), the highest predictive value for mortality was demonstrated by presepsin. Overall, presepsin was identified as a new predictor of sepsis as well as death from sepsis among patients undergoing surgery for intra-abdominal infections. These data should be confirmed in a larger cohort.