Sancaktar ME, Ağrı I, Bel Çeçen A, et al. - Since recent findings indicate that elevated neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are poor prognostic factors in sudden sensorineural hearing loss (SSNHL), researchers examined the accuracy of this assumption by taking into account the impact of cardiovascular risk (CVR) factors. Medical records of 122 individuals with SSNHL have been reviewed retrospectively and grouped into two as; patients without CVR (group 1; n = 68) and patients having CVR (group 2; n = 54). In addition, 60 control cases who did not have SSNHL were also included and grouped into two as; group 3 (n = 30) with CVR and group 4 (n = 30) healthy controls without having SSNHL or CVRs. Elevated levels of neutrophil and NLR can be regarded as strong laboratory findings showing an inflammatory response in the SSNHL diagnosis, but the involvement of CVR factors does not appear to increase the inflammatory response in SSNHL as predicted. NLR and PLR elevation may indicate better prognosis in patients with SSNHL.