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The prognostic role of IL-10 in non-severe COVID-19 with chemosensory dysfunction

Cytokine Feb 10, 2021

Locatello LG, Bruno C, Maggiore G, et al. - Researchers investigated possible clinical or immunological predictors of recovery from olfactory and gustatory dysfunction (OD/GD) in a cohort of mild/moderate hospitalized patients with COVID-19 infection. This analysis involved 119 hospitalized patients, and of those, OD/GD was present on admission in 43 (36%). A full recovery from OD and GD occurred in 60.6% and 69.2%, respectively. IL-10 level on admission was the only factor significantly related to recovery of taste; a higher prevalence of allergic respiratory disease was noted in the group who did not recover from OD and GD. Overall, experts recognized COVID-19 associated OD/GD as an inflammatory-mediated condition in which the evolution of these symptoms could be predicted by clinical and immunological parameters.

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